2024 (in English only)

1. Tatsuroh Kaneko, Asuka Oura, Yoshiki Imai, Ikue Kusumoto-Yoshida, Takuro Kanekura, Hiroyuki Okuno, Tomoyuki Kuwaki, Hideki Kashiwadani: Orexin neurons play contrasting roles in itch and pain neural processing via projecting to the periaqueductal gray. Comm Biol 7:290, 2024. DOI:10.1038/s42003-024-05997-x

 

2023 (in English only)

1. Tatsuroh Kaneko, Tomoyuki Kuwaki: The opposite roles of orexin neurons in pain and itch neural processing. Peptides 160: 170928, 2023. DOI:10.1016/j.peptides.2022.170928

2. Shigetaka Kawashima, Fan Lou, Ikue Kusumoto-Yoshida, Liying Hao and Tomoyuki Kuwaki: Activation of the rostral nucleus accumbens shell by optogenetics induces cataplexy-like behavior in orexin neuron-ablated mice. Sci Rep 13: 2546, 2023. DOI:10.1038/s41598-023-29488-x

3. Tomoyuki Kuwaki, Nobuaki Takahashi: TRPA1 channel in the airway underlies protection against airborne threats by modulating respiration and behaviour. (Symposium Review) J Physiol (accepted), 2023. DOI:10.1113/JP284076

4. Jun Kaminosono, Yuki Kambe, Akihide Tanimoto, Tomoyuki Kuwaki, Akira Yamashita: The physiological response during optogenetic-based cardiac pacing in awake freely moving mice. Front Physiol -Autonom Neurosci 14: 1130956, 2023. DOI:10.3389/fphys.2023.1130956

5. Jihao Ma, Sakurako Yanase, Lisa Udagawa, Tomoyuki Kuwaki, Ikue Kusumoto-Yoshida: Activation of neurons in the insular cortex and lateral hypothalamus caused by food restriction in mice during food anticipatory period. J Physiol Sci (2023) 73:34. DOI:10.1186/s12576-023-00892-2

 

2022 (in English only)

1. Kohei Miyata, Yoko Ikoma, Koshi Murata, Ikue Kusumoto-Yoshida, Kenta Kobayashi, Tomoyuki Kuwaki, Youichirou Ootsuka: Multifaceted roles of orexin neurons in mediating methamphetamine-induced changes in body temperature and heart rate. IBRO Neurosci Rep 12: 108-120, 2022. DOI:10.1016/j.ibneur.2022.01.002

2. Shi Zhou, Akira Yamashita, Jingyang Su, Yang Zhang, Wuyang Wang, Liying Hao, Akihiro Yamanaka, Tomoyuki Kuwaki: Activity of putative orexin neurons during cataplexy. Mol Brain 15: 21, 2022. DOI:10.1186/s13041-022-00907-w

3. Tatsuroh Kaneko, Tomoyuki Kuwaki, Hideki Kashiwadani: Hypothalamic orexinergic neurons modulate pain and itch in an opposite way: pain relief and itch exacerbation. J Physiol Sci 72: 21 (2022) DOI:10.1186/s12576-022-00846-0

4. Hideki Kashiwadani, Thomas Heinbockel, Fumiaki Imamura, Masahiro Yamaguchi, Sachiko Koyama, Kenji Kondo: Editorial: Physiology and Pathophysiology of the olfactory system. Front Neural Circuits 16: 1025087 (2022) DOI:10.3389/fncir.2022.1025087

5. Mayuko Yoshida, Koki Yamamoto, Tomoyuki Kuwaki: Positive memory increases cataplexy-like behaviors in narcolepsy mice as revealed using conditioned place preference test. BMC Neurosci 23: 82 (2022) DOI:10.1186/s12868-022-00772-2

 

2021 (in English only)

1. Tomoyuki Kuwaki, Kouta Kanno: Sexual excitation induces courtship ultrasonic vocalizations and cataplexy-like behavior in orexin neuron-ablated male mice. Comm Biol 4:165, 2021. DOI:10.1038/s42003-021-01696-z

2. Tomoyuki Kuwaki: Orexin (hypocretin) participates in central autonomic regulation during fight-or-flight response. Peptides 139:170530, 2021. DOI:10.1016/j.peptides.2021.170530

3. Shunpei Moriya, Tomoyuki Kuwaki: A13 dopamine cell group in the zona incerta is a key neuronal nucleus in nociceptive processing. Neural Regener Res 16:1415-1416, 2021. DOI:10.4103/1673-5374.300991

4. Hideki Kashiwadani, Yurina Higa, Mitsutaka Sugimura, Tomoyuki Kuwaki: Linalool odor-induced analgesia is triggered by TRPA1-independent pathway in mice. Behav Brain Funct 17: 3, 2021.DOI:10.1186/s12993-021-00176-y

5. Yurina Higa, Hideki Kashiwadani, Mitsutaka Sugimura, Tomoyuki Kuwaki: Orexiergic descending inhibitory pathway mediates linalool odor-induced analgesia in mice. Sci Rep 11: 9224, 2021. DOI:10.1038/s41598-021-88359-5

6. Akira Yamashita, Shunpei Moriya, Ryusei Nishi, Jun Kaminosono, Akihiro Yamanaka, Tomoyuki Kuwaki: Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice. Mol Brain 14: 104, 2021. DOI:10.1186/s13041-021-00818-2

7. Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Junichi Sakaguchi, Yoko Ikoma, Yoshimune Sameshima, Yuki Kambe, Akihiro Yamanaka, Tomoyuki Kuwaki: Involvement of A5/A7 noradrenergic neurons and B2 serotonergic neurons in nociceptive processing: a fiber photometry study. Neural Regener Res 17:881-886, 2021. DOI:10.4103/1673-5374.322465

8. Koyama S, Kondo K, Ueha R, Kashiwadani H, Heinbockel T: Possible Use of Phytochemicals for Recovery from COVID-19-Induced Anosmia and Ageusia. Int J Mol Sci. 2021 Aug 18;22(16):8912. doi: 10.3390/ijms22168912. PMID: 34445619

 

2020 (in English only)

1. Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Yuki Kambe, Junichi Sakaguchi, Honami Setoyama, Akihiro Yamanaka and Tomoyuki Kuwaki: Involvement of supralemniscal nucleus (B9) 5-HT neuronal system in nociceptive processing: a fiber photometry study. Molec Brain 13:14, 2020. DOI:10.1186/s13041-020-0553-1

2. Jingyang Su, Zhi Li, Akira Yamashita, Ikue Kusumoto-Yoshida, Takuto Isomichi, Liying Hao, Tomoyuki Kuwaki: Involvement of the Nucleus Accumbens in Chocolate-induced Cataplexy. Sci Rep 10: 4958, 2020.

3. Shunpei Moriya, Akira Yamashita, Daiki Masukawa, Honami Setoyama, Yunsu Hwang, Akihiro Yamanaka, Tomoyuki Kuwaki: Involvement of A13 dopaminergic neurons located in the zona incerta in nociceptive processing: a fiber photometry study. Mol Brain 13: 60, 2020. DOI:10.1186/s13041-020-00600-w

4. Shuichi Matsuda, Jun Dal Kim, Fumihiro Sugiyama, Yuji Matsuo, Junji Ishida, Kazuya Murata, Kanako Nakamura, Kana Namiki, Tatsuhiko Sudo, Tomoyuki Kuwaki, Masahiko Hatano, Koichiro Tatsumi, Akiyoshi Fukamizu, and Yoshitoshi Kasuya: Transcriptomic evaluation of pulmonary fibrosis related genes : Utilization of transgenic mice with modifying p38 signal in the lungs. Int J Mol Sci 21: 6746, 2020; doi:10.3390/ijms21186746

5. Sichong Chen, Nobuaki Takahashi,Changping Chen, Jordan L. Pauli, Chiharu Kuroki, Jun Kaminosono, Hideki Kashiwadani, Yuichi Kanmura, Yasuo Mori, Shaowu Ou, Liying Hao, Tomoyuki Kuwaki: Transient Receptor Potential Ankyrin 1 mediates hypoxic responses in mice. Front Physiol 11:576209, 2020. DOI:10.3389/fphys.2020.576209

6. Tomoyuki Kuwaki (2020) Respiratory response to airborne stress including tobacco smoke. (Abstract in English) The Autonomic Nervous System 57: 26-30.

7. Tomoyuki Kuwaki (2020) Central autonomic regulation of stress defense response. (Abstract in English) The Autonomic Nervous System 57: 157-164.

 

2019 (in English only)

1. Kengo Nomura, Takeshi Y. Hiyama, Hiraki Sakuta, Takashi Matsuda, Chia-Hao Lin, Kenta Kobayashi, Kazuto Kobayashi, Tomoyuki Kuwaki, Kunihiko Takahashi, Shigeyuki Matsui, Masaharu Noda. [Na+] increases in body fluids sensed by central Nax induce sympathetically mediated blood pressure elevations via H+-dependent activation of ASIC1a. Neuron 101: 60-75, 2018. doi:10.1016/j.neuron.2018.11.017 (see also commentary on page 3).

2. Shouhei Iwakawa, Yuichi Kanmura, Tomoyuki Kuwaki: Orexin receptor blockade-induced sleep preserves the ability to wake in the presence of threat in mice. Front Behav Neurosci 12: 327, 2019. doi: 10.3389/fnbeh.2018.00327

3. Shunpei Moriya, Akira Yamashita, Ryusei Nishi, Yoko Ikoma, Akihiro Yamanaka, Tomoyuki Kuwaki: Acute nociceptive stimuli rapidly induce the activity of serotonin and noradrenalin neurons in the brain stem of awake mice. IBRO Reports 7: 1-9, 2019. DOI:10.1016/j.ibror.2019.05.005

 

2018 (in English only)

1. Takahiro Futatsuki, Akira Yamashita, Khairunnisa Novita Ikbar, Akihiro Yamanaka, Kazunori Arita, Yasuyuki Kakihana, Tomoyuki Kuwaki: Involvement of orexin neurons in fasting- and central adenosine-induced hypothermia. Sci Rep 8: 2717, 2018. doi: 10.1038/s41598-018-21252-w

2. Yoko Ikoma, Ikue Kusumoto-Yoshida, Akihiro Yamanaka, Youichirou Ootsuka, Tomoyuki Kuwaki: Inactivation of Serotonergic Neurons in the Rostral Medullary Raphé attenuates Stress-induced Tachypnea and Tachycardia in Mice. Front Physiol (Integr Physiol) 9: 832, 2018. doi: 10.3389/fphys.2018.00832

3. Shunpei Moriya, Akira Yamashita, Shigetaka Kawashima, Ryusei Nishi, Akihiro Yamanaka, and Tomoyuki Kuwaki: Acute aversive stimuli rapidly increase the activity of ventral tegmental area dopamine neurons in awake mice. Neurosci 386: 16-23, 2018. DOI:10.1016/j.neuroscience.2018.06.027

4. Hiroki Harada, Hideki Kashiwadani, Yuichi Kanmura, Tomoyuki Kuwaki: Linalool odor-induced anxiolytic effects in mice. Front Behav Neurosci 12: 241, 2018. doi: 10.3389/fnbeh.2018.00241

5. Kengo Nomura, Takeshi Y. Hiyama, Hiraki Sakuta, Takashi Matsuda, Chia-Hao Lin, Kenta Kobayashi, Kazuto Kobayashi, Tomoyuki Kuwaki, Kunihiko Takahashi, Shigeyuki Matsui, Masaharu Noda. [Na+] increases in body fluids sensed by central Nax induce sympathetically mediated blood pressure elevations via H+-dependent activation of ASIC1a. Neuron (online), 2018. doi:10.1016/j.neuron.2018.11.017

 

2017 (in English only)

1. H. Kashiwadani, Y. Kanmura, T. Kuwaki: Application of calibrated forceps for assessing mechanical nociception with high time resolution in mice. 2017/02/18 Plos One 12(2): e0172461, DOI:10.1371/journal.pone.0172461, PMID:28212389

2. M. Hasegawa-Moriyama, K. Mukaihara, T. Yamada, T. Kuwaki, Y. Kanmura: Transient receptor potential ankyrin 1 ion channel facilitates acute inflammation induced by surgical incision in mice. Open J Anes 7: 134-145, 2017. DOI:10.4236/ojanes.2017.75014

 

2016 (in English only)

1. Ayumu Inutsuka, Akira Yamashita, Srikanta Chowdhury, Junichi Nakai, Masamichi Ohkura, Toru Taguchi, Akihiro Yamanaka: The integrative role of orexinhypocretin neurons in nociceptive perception and analgesic regulation. Sci Rep 6: 29480, 2016.

2. Kohei Miyata, Tomoyuki Kuwaki, Youichirou Ootsuka: The integrated ultradian organization of behavior and physiology in mice and the contribution of orexin to the ultradian patterning. Neurosci 334:119-133, 2016. PMID:27491480, DOI:10.1016/j.neuroscience.2016.07.041

3. Tomotsugu Yamada, Maiko Hasegawa-Moriyama, Tae Kurimoto, Takayuki Saito, Tomoyuki Kuwaki, Yuichi Kanmura: Peripheral nerve block facilitates acute inflammatory responses induced by surgical incision in mice. Regional Anesth and Pain Med 41(5): 593-600, 2016. doi:10.1097/AAP.0000000000000458, PMID:27547899

4. Hirotaka Ueda, Mayu Suga, Takakazu Yagi, Ikue Kusumoto-Yoshida, Hideki Kashiwadani, Tomoyuki Kuwaki, Shouichi Miyawaki: Vagal afferent activation induces salivation and swallowing-like events in anesthetized rats. Am J Physiol Regl Integ Compr Physiol 311: R964-R970, 2016. PMID:27707722, DOI:10.1152/ajpregu.00292.2016

5. Shogo Tashiro, Ran Yamaguchi, Sodemi Ishikawa, Takeshi Sakurai, Katsuko Kajiya, Yuichi Kanmura, Tomoyuki Kuwaki, and Hideki Kashiwadani: Odour-induced analgesia mediated by hypothalamic orexin neurons in mice. Sci Rep 6: 37129, 2016. DOI:10.1038/srep37129

6. Pascal Carrive & Tomoyuki Kuwaki: Orexin and Central Modulation of Cardiovascular and Respiratory Function. In Current Topics in Behavioral Neuroscience, pp1-40, 2016 Dec 02. Springer. PMID: 27909989, DOI:10.1007/7854_2016_46

7. Keiichi Inui, ChangPing Chen, Jordan Pauli, Chiharu Kuroki, Shogo Tashiro, Yuichi Kanmura, Hideki Kashiwadani, Tomoyuki Kuwaki: Nasal TRPA1 mediates irritant-induced bradypnea in mice. Physiological Reports 4(24) e13098, 2016. DOI:10.14814/phy2.13098

 

2015 (in English only)

1. Keiji Yamaguchi, Takahiro Futatsuki, Jumpei Ushikai, Chiharu Kuroki, Toshiaki Minami, Yasuyuki Kakihana, Tomoyuki Kuwaki: Intermittent but not sustained hypoxia activates orexin-containing neurons in mice. Resp Physiol Neurobiol 206: 11-14, 2015.

2. Kusumoto-Yoshida I, Liu H, Chen BT, Fontanini A, Bonci A: Central role for the insular cortex in mediating conditioned responses to anticipatory cues. Proc Natl Acad Sci USA 112(4): 1190-1195, 2015.

3. Tomoyuki Kuwaki: A role for orexin neurons in thermoregulation under pressure. Temperature 2(3): 379-391, DOI: 10.1080/23328940.2015.1066921

 

2014 (in English only)

1. Chiharu Kuroki, Maiko Hasegawa-Moriyama, Kohei Godai, Atsushi Yoshikawa, Akira Matsunaga, Takahiro Sato, Yuichi Kanmura, and Tomoyuki Kuwaki: Perfusion index as a possible predictor for postanesthetic shivering. J Anesth 28: 19-25, 2014.

2. Keiji Yamaguchi, Takahiro Futatsuki, Jumpei Ushikai, Chiharu Kuroki, Toshiaki Minami, Yasuyuki Kakihana, Tomoyuki Kuwaki: Intermittent but not sustained hypoxia activates orexin-containing neurons in mice. Resp Physiol Neurobiol (in press)

3. Komano-Inoue S, Manabe H, Ota M, Kusumoto-Yoshida I, Yokoyama TK, Mori K, Yamaguchi M: Top-down inputs from the olfactory cortex in the postprandial period promote elimination of granule cells in the olfactory bulb. Eur J Neurosci 40(5) :2724-2733, 2014.

 

2013 (in English only)

1. Chiharu Kuroki, Yoshiko Takahashi, Youichirou Ootsuka, Yuichi Kanmura, and Tomoyuki Kuwaki: The impact of hypothermia on emergence from isoflurane anesthesia in orexin neuron-ablated mice.Anesthesia and Analgesia 116:1001-1005, 2013.

2. Chiharu Kuroki, Maiko Hasegawa-Moriyama, Kohei Godai, Atsushi Yoshikawa, Akira Matsunaga, Takahiro Sato, Yuichi Kanmura, and Tomoyuki Kuwaki: Perfusion index as a possible predictor for postanesthetic shivering. J Anesth (in press).

3. Maiko Hasegawa-Moriyama, Tae Kurimoto, Mayo Nakama, Kohei Godai, Masayasu Kojima, Tomoyuki Kuwaki, and Yuichi Kanmura: Peroxisome proliferator-activated receptor-gamma agonist resiglitazone attenuates inflammatory pain through the iduction of heme oxygenase-1 in macrophages. Pain 154(8): 1402-1412.

4. Yoshiko Takahashi, Wei Zhang, Kohei Sameshima, Chiharu Kuroki, Ami Matsumoto, Jinko Sunanaga, Yu Kono, Takeshi Sakurai, Yuichi Kanmura, and Tomoyuki Kuwaki: Orexin neurons are indispensable for prostaglandin E2-induced fever and defence against environmental cooling in mice. J Physiol 591(22): 5623-5643, 2013.

5. Yonemitsu T, Kuroki C, Takahashi N, Mori Y, Kanmura Y, Kashiwadani H, Ootsuka Y, Kuwaki T. TRPA1 detects environmental chemicals and induces avoidance behavior and arousal from sleep. Sci Rep 3, 3100; DOI:10.1038/srep03100 (2013).

 

2012 (in English only)

1. Tomoyuki Kuwaki & Wei Zhang: Orexin Neurons and Emotional Stress. in Sleep Hormones (Vitamins and Hormones vol. 89), Academic Press, New York, pp.135-158, 2012.

 

2011 (in English only)

1. Nobuaki Takahashi, Tomoyuki Kuwaki, Shigeki Kiyonaka, Tomohiro Numata, Daisuke Kozai, Yusuke Mizuno, Shinichiro Yamamoto, Shinji Naito, Ellen Knevels, Peter Carmeliet, Toru Oga, Shuji Kaneko, Seiji Suga, Toshiki Nokami, Jun-ichi Yoshida & Yasuo Mori: TRPA1 underlies a sensing mechanism for O2. Nature Chemical Biology 7: 701-711, 2011.

2. Kobayashi-Torii M, Takahashi Y, Sunanaga J, Fujita M, Lee EY, Ichimaru Y, Fujita T, Kanmura Y, Kuwaki T: Possible participation of extracellular calcium-sensing receptor in blood pressure regulation in rats. Brain Res 1367: 181-187, 2011.

3. Kuwahata S, Miyata M, Fujita S, Kubozono T, Shinsato T, Ikeda Y, Hamasaki S, Kuwaki T, Tei C: Improvement of autonomic nervous activity by Waon Therapy in patients with chronic heart failure. J Cardiol. 57: 100-106, 2011.

4. Nagata-Kuroiwa R, Furutani N, Hara J, Hondo M, Ishii M, Abe T, Mieda M, Tsujino N, Motoike T, Yanagawa Y, Kuwaki T, Yamamoto M, Yanagisawa M, Sakurai T: Critical role of neuropeptides B/W receptor 1 signaling in social behavior and fear memory. Plos One 6(2): e16972.

5. Kuwaki T: Orexin links emotional stress to autonomic functions. Autonom Neurosci 161: 20-27, 2011.

6. Kuwaki T: A key role of orexin (hypocretin) neurons in the fight-or-flight response. Physiology News 83 (summer 2011): 15-17, 2011.

7. Setoguchi D, Nakamura M, Yatsuki H, Watanabe E, Tateishi Y, Kuwaki T, Oda S: Experimental examination of anti-inflammatory effects of a 5-HT3 receptor antagonist, tropisetron, and concomitant effects on autonomic nervous function in a rat sepsis model. International Immunopharmacology 11:2073-2078, 2011.

8. Ootsuka Y, Kulasekara K, de Menezes RC, Blessing WW: SR59230A, a beta-3 adrenoceptor antagonist, inhibits ultradian brown adipose tissue thermogenesis and interrupts associated episodic brain and body heating. Am J Physiol Regul Integr Comp Physiol 301: R987-R994, 2001.

9. Blessing E, Kader L, Ootsuka Y, Blessing WW, Pantelis C: Atypical antipsychotics cause an acute increase in cutaneous hand blood flow in patients with schizophrenia and schizoaffective disorder. Aust N Z J Psychiatry 45: 646-653, 2011.

10. Blessing W, Mohammed M, Ootsuka Y: Heating eating: Brown adipose tissue thermogenesis precedes food ingestion as part of the ultradian basic rest-activity cycle in rats. Physiol Behav 105: 966-974, 2011.

 

2010 (in English only)

1. Kuwaki T, Zhang W: Autonomic malfunctions in mice model of narcolepsy. In Narcolepsy: Symptoms, Causes and Diagnosis and Treatment. (Eds: Guillermo Santos & Lautar Villalba) Nova Science Publishers, NY. 2010, pp.1-33. ISBN: 978-1-60876-645-1

2. Mori T, Ito S, Kuwaki T, Yanagisawa M, Sawaguchi T: Monoaminergic neuronal changes in orexin deficient mice. Neuropharmacology 58: 826-832, 2010.

3. Kuwaki, T: Hypothalamic modulation of breathing. Adv Exp Med Biol 669 (New Frontiers in Respiratory Control): 243-247, 2010.

4. Kuwaki T, Li A, Nattie E: State-dependent central chemoreception: A role of orexin. Resp Physiol Neurobiol 173: 223-229, 2010.

5. Kuwaki T, Zhang W: Orexin neurons as arousal-associated modulators of central cardiorespiratory regulation. Resp Physiol Neurobiol 174 (Special issue "Central cardiorespiratory regulation: physiology and pathology"): 43-54, 2010.

6. Zhang W, Sunanaga J, Takahashi Y, Mori T, Sakurai T, Kanmura Y, Kuwaki T: Orexin neurons are indispensable for stress-induced thermogenesis in mice.J Physiol (London) 588(21): 4117-4129, 2010. (Commentary: R. McAllen: The peptide or the neuron? J Physiol 588.21: 4067-4068, 2010.)

7. Kuwaki T: Orexin links emotional stress to autonomic functions. Autonom Neurosci(ISAN2009 special issue) (in press)

8. Kuwahata S, Miyata M, Fujita S, Kubozono T, Shinsato T, Ikeda Y, Hamasaki S, Kuwaki T, Tei C: Improvement of autonomic nervous activity by Waon Therapy in patients with chronic heart failure. (in press) J Cardiol. 2010 Sep 28. [Epub ahead of print]

9. Kobayashi-Torii M, Takahashi Y, Sunanaga J, Fujita M, Lee EY, Ichimaru Y, Fujita T, Kanmura Y, Kuwaki T: Possible participation of extracellular calcium-sensing receptor in blood pressure regulation in rats.Brain Res (in press) DOI: 10.1016/j.brainres.2010.10.013

10. McAllen RM, Tanaka M, Ootsuka Y, McKinley MJ: Multiple thermoregulatory effectors with independent central controls, Eur J Appl Physiol 109:27-33, 2010.

 

2009 (in English only)

1. Sakakibara I, Fujino T, Ishii M, Tanaka T, Shimosawa T, Miura S, Zhang W, Tokutake Y, Yamamoto J, Awano M, Iwasaki S, Motoike T, Okamura M, Inagaki T, Kita K, Ezaki O, Naito M, Kuwaki T, Chohnan S, Yamamoto T, Hammer RE, Kodama T, Yanagisawa M, and Sakai J: Fasting-Induced Hypothermia and Reduced Energy Production in Mice Lacking Acetyl-CoA Synthetase 2. Cell Metab 9(2): 191-202, 2009.

2. Kuwaki T, Zhang W: Orexin-containing neuron contributes stress-induced thermogenesis. Korean J Physiol Pharmacol 13(Suppl I): 172-174, 2009.

3. Zhang W, Zhang N, Sakurai T, Kuwaki T: Orexin neurons in the hypothalamus mediate cardiorespiratory responses induced by disinhibition of the amygdala and bed nucleus of the stria terminalis. Brain Res 1262: 25-37, 2009.

4. Sunanaga J, Deng BS, Zhang W, Kanmura Y, Kuwaki T: CO2 activates orexin-containing neurons in mice. Resp Physiol Neurobiol 166(3): 184-186, 2009.

5. Toyama S, Sakurai T, Tatsumi K, Kuwaki T: Attenuated phrenic long-term facilitation in orexin neuron-ablated mice. Resp Physiol Neurobiol 168(3): 295-302, 2009.

6. Mori T, Ito S, Kuwaki T, Yanagisawa M, Sawaguchi T: Monoaminergic neuronal changes in orexin deficient mice. Neuropharmacology. 2009 Aug 22. [Epub ahead of print]

7. Ootsuka Y, de Menezes RC, Zaretsky DV, Alimoradian A, Hunt J, Stefanidis A, Oldfield BJ, Blessing WW.: Brown adipose tissue thermogenesis heats brain and body as part of the brain-coordinated ultradian basic rest-activity cycle. Neuroscience 164: 849-861, 2009.

 

2008 (in English only)

1. Kuwaki T, Zhang W, Nakamura A, Deng BS: Emotional and state-dependent modification of cardiorespiratory function: role of orexinergic neurons. Autonom Neurosci: Basic Clin 142: 11-16, 2008.

2. Kuwaki T, Zhang W: Emotional Modification of the Cardiorespiratory Regulation System. Tzu Chi Med J 20(2): 82-90, 2008.

3. Terada J, Nakamura A, Zhang W, Yanagisawa M, Kuriyama T, Fukuda Y, Kuwaki T: Ventilatory long-term facilitation in mice can be observed both during sleep and wake periods and depends on orexin. J Appl Physiol 104(2): 499-507, 2008.

4. Kuwaki T: Orexinergic modulation of breathing across vigilance states. Resp Physiol Neurobiol 164(1-2: Special Issue: Neurochemistry of Respiratory Control): 204-212, 2008.