研究実績

145
2
2021

RLTPR Q575E: A novel recurrent gain-of-function mutation in patients with adult T-cell leukemia/lymphoma.
Uchida Y, Yoshimitsu M, Hachiman M, Kusano S, Arima N, Shima K, Hayashida M, Kamada Y, Nakamura D, Arai A, Tanaka Y, Hara H, Ishitsuka K.
Eur J Haematol. 106(2):221-229. (2021)
PMID: 33098696

1
2021

Correlation of hepatitis C virus-mediated endoplasmic reticulum stress with autophagic flux impairment and hepatocarcinogenesis.
Honma Y, Miyagawa K, Hara Y, Hayashi T, Kusanaga M, Ogino N, Minami S, Oe S, Ikeda M, Hino K, Harada M.
Med Mol Morphol. (2021)
PMID: 33386512

1
2020

Study of multiple genetic variations caused by persistent hepatitis C virus replication in long-term cell culture.
Kato N, Ueda Y, Sejima H, Gu W, Satoh S, Dansako H, Ikeda M, Shimotohno K.
Arch Virol. 165(2):331-343. (2020)
PMID: 31832864

3
2019

Pyrimidotriazine derivatives as selective inhibitors of HBV capsid assembly.
Toyama M, Sakakibara N, Takeda M, Okamoto M, Watashi K, Wakita T, Sugiyama M, Mizokami M, Ikeda M, Baba M.
Virus Res. 271:197677. (2019)
PMID: 31376401

2
2019

Interaction of phospholipid scramblase 1 with the Epstein-Barr virus protein BZLF1 represses BZLF1-mediated lytic gene transcription.
Kusano S, Ikeda M.
J Biol Chem. 294(41):15104-15116. (2019)
PMID: 31434743

1
2019

Acidic polysaccharides isolated from marine algae inhibit the early step of viral infection.
Ueno M, Nogawa M, Siddiqui R, Watashi K, Wakita T, Kato N, Ikeda M, Okimura T, Isaka S, Oda T, Ariumi Y.
Int J Biol Macromol. 124:282-290. (2019)
PMID: 30452989

1
2018

Regulation of interferon signaling and HCV‑RNA replication by extracellular matrix.
Kuwashiro T, Iwane S, Jinghe X, Matsuhashi S, Eguchi Y, Anzai K, Fujimoto K, Mizuta T, Sakamoto N, Ikeda M, Kato N, Ozaki I.
Int J Mol Med. 42(2):957-965. (2018)

2
2018

Multiple antiviral activities of the antimalarial and anti-hepatitis C drug candidates N-89 and N-251.
Ueda Y, Gu W, Dansako H, Kim HS, Yoshizaki S, Okumura N, Ishikawa T, Nishitsuji H, Kato F, Hishiki T, Satoh S, Ishii K, Masuda M, Shimotohno K, Ikeda M, Kato N.
Biochem Biophys Rep. 15:1-6 (2018)

3
2018

Dual effects of the Nrf2 inhibitor for inhibition of hepatitis C virus and hepatic cancer cells.
Murakami Y, Sugiyama K, Ebinuma H, Nakamoto N, Ojiro K, Chu PS, Taniki N, Saito Y, Teratani T, Koda Y, Suzuki T, Saito K, Fukasawa M, Ikeda M, Kato N, Kanai T, Saito H.
BMC Cancer. 18(1):680 (2018)

4
2018

Complete Sequences of the Human T-Cell Leukemia Virus Type 1 Proviral Genomes from Newly Established Adult T-Cell Leukemia Cell Lines in Oita Prefecture, Japan.
Fukumoto T, Ikebe E, Ogata M, Kohno K, Kuramitsu M, Sato Y, Fife N, Matsumoto T, Yahiro T, Ikeda M, Kusano S, Okayama A, Hori M, Hijiya N, Tsukamoto Y, Hirashita Y, Moriyama M, Ahmed K, Hasegawa H, Nishizono A, Saito M, Iha H.
Genome Announc. 6(25) (2018)

1
2017

Evaluation of preclinical antimalarial drugs, which can overcome direct-acting antivirals-resistant hepatitis C viruses, using the viral reporter assay systems.
Ueda Y, Dansako H, Satoh S, Kim HS, Wataya Y, Doi H, Ikeda M, Kato N.
Virus Res. 235: 37- 48 (2017)

2
2017

Ribavirin suppresses hepatic lipogenesis through inosine monophosphate dehydrogenase inhibition:
involvement of adenosine monophosphate-activated protein kinase-related kinasesand retinoid X receptor α.
Satoh S, Mori K, Onomura D, Ueda Y, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.
Hepatol Commun. 1(6):550-63 (2017)

1
2016

Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative.
Ito W, Toyama M, Okamoto M, Ikeda M, Watashi K, Wakita T, Hashimoto Y, Baba M.
Antivir Chem Chemother. 24(5-6):148-154 (2016)

2
2016

The cyclic GMP-AMP synthetase-STING signaling pathway is required for both the innate immune response against HBV and the suppression of HBV assembly.
Dansako H, Ueda Y, Okumura N, Satoh S, Sugiyama M, Mizokami M, Ikeda M, Kato N. 
FEBS J. 283(1):144-156 (2016)

3
2016

Molecular mechanism underlying the suppression of CPB2 1 expression caused by persistent hepatitis C virus RNA replication.
Sejima H, Satoh S, Dansako H, Honda M, Kaneko S, Ikeda M, Kato N.
Acta Med Okayama 70(2):75-88 (2016)

4
2016

Rab13 is involved in the entry step of hepatitis C virus infection. 
Takeda MIkeda M, Satoh S, Dansako H, Wakita T, Kato N. 
Acta Med Okayama 70(2):111-118

1
2015

Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells.
Okumura NIkeda M, Satoh S, Dansako H, Sugiyama M, Mizokami M, Kato N.
FEBS Lett. 589(10): 1112-8 (2015)

2
2015

Annexin A1 negatively regulates viral RNA replication of hepatitis C virus.
Hiramoto H, Dansako H, Takeda M, Satoh S, Wakita T, Ikeda M, Kato N.
Acta Medica Okayama 69(2): 71-8 (2015)

3
2015

Establishment of hepatitis C virus RNA-replicating cell lines possessing ribavirin-resistant phenotypes.
Satoh S, Mori K, Ueda Y, Sejima H, Dansako H, Ikeda M, Kato N.
PLOS ONE 10(2): e0118313 (2015)

4
2015

I-mfa domain proteins specifically interact with HTLV-1 Tax and repress its transactivating functions.
Kusano S, Yoshimitsu M, Hachiman M, Ikeda M
Virology
, 486: 219-227 (2015)

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